According to MayoClinic.com, people with albinism are at an increased risk for skin cancer because melanin acts as a natural sunblock, protecting your skin from the powerful UV rays of the sun. Melanin in the epidermis protects dermis and other internal organs against exposure to ultraviolet rays and its damaging effects. We invite you to visit your doctor if you have any type of condition or pain. In the… The type of melanin pigment (eumelanin or pheomelanin) produced and their relative proportion in the skin decides one's skin color. The most common form of inducible pigmentation is tanning, which occurs in response to UV exposure, particularly UVA wavelengths. Melanin is the pigment responsible for the color of the hair, skin, and iris. For example, tyrosinase-related protein-1 (TRP-1) is reported to be 2.6 times higher in darker African and Indian skin types compared with lighter Chinese, Mexican, and Caucasian skin (22). Birds and mammals possess these pigment cells, which are found mainly in the epidermis, though they occur elsewhere—e.g., in the matrix of the hair.Melanocytes are branched, or dendritic, and their dendrites are used to transfer pigment granules to adjacent epidermal cells. However, a lack or excess of this component in our body can lead to skin problems and other issues related to the hair or eyes. Differences in levels of melanin production have been reported between the different skin types and in vitro cultures of melanocytes obtained from black skin donors produce higher levels of melanin when compared with those obtained from Caucasian skin. Pheomelanin is the pigment found in red hair. Melanocyte, specialized skin cell that produces the protective skin-darkening pigment melanin. It also occurs in the zona reticularis of the adrenal gland. However, a lack or excess of this component in our body can lead to skin problems and other issues related to the hair or eyes. Melanin component is a mixture of melanin classes, black–brown ‘eumelanin’ and yellow–red ‘pheomelanin’ in a ratio of 4∼3 to 1. Melanin-containing cells, including catecholaminergic (CA) cells in the brain and melanocytes of the hair and skin, pigment cells in the inner ear, iris, and choroid of the eye, originate from the neural crest. Thus a lack of tyrosinase results in albinism (lack of melanin pigmentation), and sheep and cattle with copper deficiency have defective tyrosinase and fading of coat color. what happens when melanin levels decrease, How To Prevent The Spread of Genital Warts, What Are The Best Shoes to Prevent Varicose Veins, What Is The Normal Range Of Lymphocyte Count, How Many Calories To Eat Per Day Based On Age, How Long Does it Take for Prednisone to Work, What Does An Elevated Lymphocyte Count Mean, Causes of Pain in Right Side of your Stomach. You're probably wondering what the function of melanin is. The proportion of melanocyte molecules that are in our body will determine our pigmentation. Another function of hair follicle is giving color to your hair. The natural color of our hair depends upon the distribution, type and amount of melanin in the middle layer of the hair shaft or cortex. Melanin is produced by melanocytes situated in the basal layer of the epidermis. Your genes, inherited from your parents, largely dictate how much melanin you make; people with dark skin have more melanin than people with fair (light-colored) skin do. Melanin is a polymer of variable forms that absorbs light across a broad spectrum of wavelengths, absorbing both UVA (tanning UV wavelengths) and the shorter wavelength, higher energy UVB (sunburn wavelengths; 3). Eumelanin is composed of indole derivatives produced by autooxidation of dopamine, whereas pheomelanin contains benzothiazine molecules from incorporated cysteine or GSH with dopamine–quinone derived from dopamine by autooxidation. 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